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Improvement of Pustulosis Palmaris et Plantaris by Periodontal Infection Control in a Patient with Chronic Periodontitis by Osamu Murai, Daisuke Sasaki, Yoshinori Ando, Akira Fujimura, Hiromi Oikawa, Nagisa Suwa, Daisuke Watabe, Fumihiko Maeda, Kohki Endo, Takashi Yaegashi, Toshihide Akasaka, Koji Naruishi

Background: Pustulosis palmaris et plantaris (PPP) is a chronic, inflammatory, autoimmune-type disease characterized by sterile pustules of skin. The skin inflammation is influenced by several factors such as drugs, sunlight, metabolic and psychogenic factors as well as metal allergy. Here, we report a rare case that intensive periodontal treatment might have contributed to the improvement of skin inflammation.
Results: Skin inflammation regressed 1 month after intensive periodontal treatment. Both CD4/CD8 ratio and % of B cells in the blood sample were slightly decreased corresponding to the improvement of periodontal inflammation.
Conclusions: Infection control of periodontal lesions might be one of attractive therapeutic targets in management of PPP.

DOI: Clin. Lab. 2012;58:323-327