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Background: To investigate the markers of systemic function by using laboratory parameters as life parameters.
Methods: Lymphocyte count, albumin, and creatinine levels were measured using automatic analyzers in young, healthy individuals (20–39 years) and senior individuals (80–95 years) as well as in terminally ill patients. We developed a mathematic model and scoring system (indexes of systemic function, ISF) based on the above mentioned biological markers.
Results: ISF scores were significantly lower in the senior group (P < 0.05) than those in the young, healthy group. A significant decrease was observed in the ISF of the terminally ill group and that of the senior group (P < 0.05).
Conclusions: Our results suggest that the ISF scoring system of systemic function can be used to objectively evaluate the systemic function in individuals with different health statuses.
DOI: Clin. Lab. 2010;56:223-225
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