Clinical Laboratory

You have to be registered and logged in for purchasing articles.

Abstract	A Rare Case of Cefoperazone/Sulbactam-Induced Significant Prolongation of INR by Ying Yu, Qing Wang

	Background: Cefoperazone/sulbactam (CPZ/SAM) is a first-line antibacterial drug in clinical practice. Methods: This article reports a case of extreme elevation of INR due to the use of CPZ/SAM four days. After drug withdrawal and administration of fresh frozen plasma, the coagulation function returned to normal. Results: The INR results were extremely elevated, which is believed to be caused by taking CPZ/SAM. Conclusions: When patients take CPZ/SAM anti-infection therapy, the patient's coagulation function should be closely monitored for the prevention of the occurrence of adverse reactions. DOI: 10.7754/Clin.Lab.2025.250612

Abstract