Abstract
|
Allergic Bronchopulmonary Mycosis with Eosinophilia Caused by Schizophyllum Infection
by Xin H. Yuan, Qian C. Chen, Yan Wang, Jian H. Hao, Ai J. Guo, Jia B. Zhang, Ai S. Fu, Yan L. Ge
|
|
|
Background: As an opportunistic pathogenic fungus, Schizophyllum has been rarely reported to infect humans. By reporting a case of definite diagnosis of Schizophyllum infection, we aim to improve clinicians' understanding of this bacterium.
Methods: By reporting a case with cough and sputum as the main manifestations, after empirical antiinfective chest CT suggesting a more progressive inflammatory lesion and a mass-like lesion in the paratracheal area of the main airways, a diagnosis of Schizophyllum infection was finally made by bronchoscopy with the delivery of metagenomic next-generation sequencing (mNGS).
Results: The patient was finally diagnosed with rare Schizophyllum infection. After antifungal treatment, the symptoms improved, and the patient was discharged.
Conclusions: Although Schizophyllum is a rare fungal infection, it should be taken seriously in patients with diabetes or who are immunocompromised. At the same time, mNGS plays a key role in the detection of rare and emerging pathogens, which is worthy of clinical interest.
DOI: 10.7754/Clin.Lab.2024.240235
|
