Abstract

Background: Chronic eosinophilic leukemia (CEL) is a rare invasive disease characterized by non-specific cytogenetic abnormalities or elevated mother cells, poor prognosis, and a high risk of conversion to acute leukemia.
Methods: We described the data of a patient with CEL-NOS.
Results: This case is a CEL-NOS with four mutations in CSF3R-T618I, DNMT3A Q816, ASXL1, and IDH2.
Conclusions: The patient rapidly evolves into secondary acute myeloid leukemia (AML).

DOI: 10.7754/Clin.Lab.2023.230924