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Abstract |
Upregulation of Toll-Like Receptors 2, 5, 7, and 9 in the Cervical Epithelial Cells of Iranian Women Infected with High-Risk Human Papilloma Virus |
Background: Toll-like receptors (TLRs) play dual roles against viruses, including defense against the viruses and induction of the viral-related cancers. High risk human papilloma viruses (HPVs) play key roles in induction of HPV-related cancers. The molecules that are upregulated by the high-risk viruses can be considered as the candidate to induce the cancers. This project was designed to evaluate expression of TLR1-9 in the women infected with HPV-high risk genotypes.
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