Background: The systematic detection of HIV, hepatitis B (HBV) and C (HCV) viruses in any blood donor has been in effect at the University hospital of Kinshasa since 2005. However, no data on the monitoring of blood donors is available today. The purpose of this thesis was to draw up the sero-epidemiological assessment of the afore-mentioned virus during the period 2014 - 2018.
Methods: This is an observational study conducted in the University Hospital of Kinshasa donor population.
Results: A total of 9,128 blood donors were admitted to the Kinshasa University Clinics Blood Bank during the period from 01/01/2014 to 12/31/2018 for 11,054 blood donations. The highest attendance (50%) of blood donors was observed in 2014 and 2015. On the other hand, 2018 (11.9%; n = 1,085) was that of the lowest frequency of blood donors. The mean age of the blood donors was 34.72 ± 10.66 years. The minimum and maximum age corresponded to 16 years and 65 years, respectively. The median age was 34 years (interquartile range (IQR): 27 - 40 years). The majority of the study population (75%; n = 6,841) were at most 40 years old. There were significantly more male blood donors (77.3%; n = 7,060) than female blood donors (22.7%; n = 2,066). The difference between the two gender proportions was statistically significant (p < 0.0001) at risk α = 5%. The male/female gender ratio was 3:4.
The seroprevalence of HIV, HBV, HCV and Treponema pallidum was estimated at 2.6% (n = 237), 4.7% (n = 429), 3.3% (n = 297) and 0.4% (n = 33), respectively. A total of 927 (10.16%) donors were infected with at least one agent transmissible by blood transfusion.
Conclusions: The present surveillance proves that infectious transfusion safety in Kinshasa is still very low.