You have to be registered and logged in for purchasing articles.


Detection of Cytomegalovirus Antibodies in the Serum of Hemodialysis Patients by Mohamed N. Ibrahim, Mohamed S. Alhadi, Waleed Y. Elbadawy, Majed S. Al-Sharari, Hadeel M. Al-Ruwali, Tahani M. Al-Anazi

Background: The infection with Cytomegalovirus (CMV) is one of the main causes of morbidity and mortality in hemodialysis patients.
Objectives: This study aims to investigate CMV serostatus in renal failure patients undergoing hemodialysis.
Methods: The study included a total of 134 cases (55 females and 79 males) with an age range of 35 - 68 years (mean age 37.43 ± 13.42 years). HCMV-IgG and IgM were determined in subjects' sera.
Results: Eighty-seven out of 134 (65%) were undergoing hemodialysis, while 47 (35%) had normal kidney functions without HCV infection. Sixty-eight (78.2%) and 31 (35.6%) cases out 87 hemodialysis patients were positive for CMV-IgG and IgM antibodies, respectively. No significant differences were noted between females and males in terms of seroprevalence rates. High rate of positive CMV-IgG was observed among hemodialysis patients who were 48 - 64 years old.
Conclusions: Our data suggest that seroprevalence of CMV antibodies among hemodialysis cases is high and causes complications for these patients.

DOI: 10.7754/Clin.Lab.2021.211107