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The Role of the NLR and PLR in Urinary Tract Infection by Zeynep Asik

Background: Urinary tract infections are common diseases especially seen in bedridden patients. Urine culture, which is the gold standard in the diagnosis of this disease, is an expensive examination, results take a long time, and not available in every center. The objective of this study is to explain the role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in urinary tract infections.
Methods: For the research, urine culture, NLR, and PLR values of 406 patients, who had urinary tract infections and were registered in Antalya Training and Research Hospital home health services unit, were examined from the health records. In the study, NLR and PLR were studied in blood. In addition, NLR and PLR values of 414 participants were examined as the control group.
Results: The mean NLR and PLR values of the participants with urinary tract infection were 4.624 ± 5.818 and 176.645 ± 110.051. The mean NLR and PLR values of the participants without urinary tract infection were 2.117 ± 1.266 and 121.945 ± 53.735. NLR and PLR values of the participants with and without urinary tract infection were compared, and the result was statistically significant (p = 0.000 and p = 0.000, respectively). Urine culture, NLR and PLR values were compared in the patients with urinary system infection. NLR and PLR were lower in the patients with positive urine culture than the patients with negative urine culture; however, the result was statistically insignificant (p = 0.610 and p = 0.702, respectively).
Conclusions: According to our results, NLR and PLR were higher in the patients with urinary tract infection than the in healthy volunteer control group. Therefore, it is thought that the clinical judgement of symptoms and complaints comes first and then the NLR and PLR can be used as inflammatory markers in patients with urinary tract infection.

DOI: 10.7754/Clin.Lab.2021.210133