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Plasminogen Activator Inhibitor in Patients with Acute Myocardial Infarction and Re-Infarction in Syndrome X by Mirka Illić, Nada Majkić-Singh, Katarina Lalić

Plasminogen activator inhibitor was determined in myocardial infarction and re-infarction patients along with other parameters relevant for the Syndrome X, such as triglycerides, HDL-cholesterol and body mass index. Plasminogen activator inhibitor was determined in 58 patients with myocardial infarction and 18 patients with reinfarction as well as in 57 healthy individuals. Significantly higher plasminogen activator inhibitor values were found in re-infarction patients (6.53 ± 0.39 U/mL) than in myocardial infarction patients (4.32 ± 0.19 U/mL), whereas the values were significantly higher in both groups in comparison to healthy individuals (2.81 ± 0.74 U/mL). Triglyceride values were also significantly higher in myocardial infarction (2.05 ± 0.1 mmol/L) and reinfarction patients (2.02 ± 0.99 mmol/L) than in healthy individuals (1.35 ± 0.58 mmol/L), alhough the difference between the triglyceride values obtained for myocardial infarction and re-infarction patients was not statistically significant. HDL-cholesterol values for myocardial infarction (1.18 ± 0.04 mmol/L) and re-infarction (1.14 ± 0.18 mmol/L) patients were significantly lower than in healthy individuals (1.46 ± 0.5 mmol/L). However, the difference was not statistically significant between the myocardial infarction and the re-infarction group. The difference in body mass index between myocardial infarction (26.65 ± 0.39 kg/m2) and re-infarction (25.49 ± 0.39 kg/m2) patients and healthy individuals (24.45 ± 3.4 kg/m2) was evidenced

DOI: Clin. Lab. 2002:48:125-128