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Association Among Glycemic Biomarkers in Korean Adults: Hemoglobin A1c, Fructosamine, and Glycated Albumin by Rihwa Choi, Mi-Jung Park, Sukjung Lee, Sang Gon Lee, Eun Hee Lee

Background: We aimed to investigate the associations between glycemic biomarkers (hemoglobin A1c [HbA1c], fructosamine, and glycated albumin [GA]) in Korean adults.
Methods: We retrospectively reviewed data for HbA1c, fructosamine, and glycated albumin between August 28, 2017, and June 30, 2020, to investigate the association between HbA1c and fructosamine and between HbA1c and GA.
Results: Overall, 961 fructosamine and 142 GA tests concurrently measured HbA1c. The equations were HbA1c (%) = 0.0175 x fructosamine (µmol/L) + 1.6255 and HbA1c (%) = 0.2029 x GA + 2.8102, respectively. The absolute difference between estimated and measured HbA1c ranged from -3.4% to 2.1% HbA1c with the fructosamine equation and -3.2% to 2.8% HbA1c with the GA equation.
Conclusions: Fructosamine and GA may be useful adjuncts to HbA1c in Korean patients.

DOI: 10.7754/Clin.Lab.2020.201133