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Abstract |
Performance of Elecsys® Toxo IgG and IgM Immunoassays |
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Roche Diagnostics has developed two new rapid and fully automated assays for the detection of Anti-Toxo-IgG and Toxo-IgM antibodies from human sera and plasma. The performance evaluation of the Elecsys® Toxo IgG resulted in a sensitivity of 100% and a specificity of 99.91% showing that this assay allows a very sensitive and specific detection of Toxo IgG antibodies with an excellent discrimination of positive and negative results. The performance evaluation of the Elecsys® Toxo IgM assay revealed a sensitivity of 100% and a specificity of 99.11% after resolution. Less reactivity towards persistent Toxo IgM antibodies in samples from Toxoplasma infections > 3 months was found with Elecsys® Toxo IgM. The performance evaluation data demonstrate that the Elecsys® Toxo IgG and Elecsys® Toxo IgM assays are reliable tools in routine diagnostics of Toxoplasma infections with the additional advantage of a high throughput on fully automated analyzers MODULAR ANALYTICS Serum Work Area. |
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