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Evaluation of a new Strongyloides ELISA IgG Test Kit by Kamran Kadkhoda, Bill Gibson Jr

Background: Strongyloides stercoralis poses a significant clinical and public health challenge not only in endemic regions but also in non-endemic regions associated with travel. Ruling out this infection is essential in immuno-compromised hosts given the high probability of reactivation and mortality.
Methods: In this study we compared an ELISA based on two recombinant antigens in the United States with a highly sensitive and specific reference serological test.
Results & Conclusion: There was 100% agreement between the two methods. ELISA assays based on Strongyloides stercoralis recombinant antigens has the potential to improve specificity. Further studies are warranted.

DOI: 10.7754/Clin.Lab.2020.200319