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Spurious Low WBC Count from Sysmex XN3000: a Case Report by Changzhi Xu, Yanhua Yi, Donglin Zhu, Zhizhi Xie, Xiaojie Li, Yun Xi

Background: We present a case of spurious low WBC count in a liver transplant patient. The patient is a 56-year-old man with liver cancer.
Methods: His routine blood test revealed a decrease in WBC count: 0.03 x 109/L compared to 19.30 x 109/L before. The WBCs in the blood smear appeared higher than that reported by the XN without any aggregation. We diluted the blood sample to 1:7 with the DCL of the XN.
Results: The diluted result matches the blood smear.
Conclusions: Dilution mode may be a good choice when there is WNR and WDF discordance, and a smear must be reviewed.

DOI: 10.7754/Clin.Lab.2019.190409