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Early Detection of a Colorectal Carcinoma in an Asymptomatic Patient Using a Combined DNA Stool Test by Asef Amani, Mathias M. Weber, Christian Marko

Background: Modern, simple stool tests could close the gap regarding the recognition rate (sensitivity) between the current test methods and colonoscopy.
Methods: Here we report a case of a 68-year-old asymptomatic patient, who applied an innovative combined DNA stool test.
Results: Due to a positive KRAS mutation, a colonoscopy was performed and an invasive adenocarcinoma was diagnosed. After colonoscopical resection in two steps pathological findings could not be identified anymore. All further parameters, including KRAS, stayed continuously negative.
Conclusions: In this case report, it was demonstrated that a combined DNA stool test can also be successfully applied as alternative diagnostic tool.

DOI: 10.7754/Clin.Lab.2019.190213