Clinical Laboratory

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Abstract	High Serum Neuron-Specific Enolase (NSE) Level Firstly Ignored as Normal Reaction in a Small Cell Lung Cancer Patient: a Case Report and Literature Review by Yan L. Ge, Cong H. Liu, Meng H. Wang, Xiao Y. Zhu, Qian Zhang, Zhen Z. Li, Hong L. Li, Zi Y. Cui, Hai F. Zhang, Xue Zhang, Hua L. Yu, Ai S. Fu, Hong Y. Wang

	Background: High serum neuron-specific enolase (NSE) level has been in use as a tumor marker; however, some physicians may ignore NSE levels in serum, especially when the patients are asymptomatic. Here we report a case that a 51 year old female patient with no respiratory symptoms who had a NSE level which increased extremely over three months and was eventually diagnosed small cell lung cancer (SCLC). Methods: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in right pulmonary hilar enlarged lymph node was performed for diagnosis. Results: EBUS showed right pulmonary hilar lymph node enlargement. A TBNA biopsy histopathology diagnosed SCLC. Conclusions: We should pay attention to high serum NSE levels, especially when the index increased extremely over a short time. DOI: 10.7754/Clin.Lab.2018.180703

Abstract