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Does Adenovirus and Coxsackie B Virus Infection Play a Role in Tracheobronchopathia Osteochondroplastica (TO) by Yan L. Ge, Cong H. Liu, Meng H. Wang, Zhen Z. Li, Xue Zhang, Hua L. Yu, Ai S. Fu, Hong Y. Wang

Background: Tracheobronchopathia osteochondroplastica (TO) is a rare benign disease. We report a case of TO.
Methods: Chest CT scan and bronchoscope with biopsy was performed for diagnosis and blood tests explored for the latent etiology.
Results: Chest CT scan and bronchoscopic images showed multiple nodular protrusions in the trachea and main bronchi. Histopathology demonstrated sub-mucosal ossification and inflammatory cell infiltration. Laboratory inspection showed adenovirus and coxsackie B virus IgM antibodies were positive.
Conclusions: The patient recently had a virus infection and inflammation was observed in histopathology, which indicated adenovirus and coxsackie B virus may play a role in the occurrence or exacerbation of TO.

DOI: 10.7754/Clin.Lab.2018.180618