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Abstract

Rapidly Progressive, Fata Infection Caused by Bacillus Cereus in a Patient with Acute Lymphoblastic Leukemia by Jing-Wen Zhang, Yun-Xin Zeng, Jia-Yin Liang, Ling Zhang, Xin-Bao Zhao, Jian-Hua Pan, Ruo-Zhi Xiao

Background: We herein report a fatal case of fulminant septicemia caused by Bacillus cereus in a 49-year-old female with T-cell acute lymphoblastic leukemia receiving chemotherapy.
Methods: Her two blood culture sets were positive for Gram-positive, rod-shaped bacterium. Bacillus cereus was identified by high-throughput MALDI-TOF mass spectrometry and 16S ribosomal RNA gene sequencing.
Results: The patient died within 12 hours from the onset of B cereus infection.
Conclusions: Patients with acute leukemia presented with fever and unexplained multiple organ lesions, especially accompanied by CNS symptoms, should alert to the possibility of Bacillus cereus infection.

DOI: 10.7754/Clin.Lab.2018.180528