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Abstract |
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We studied the significance of discrepancies in correlation between serum γ-globulin levels electrophoretically estimated and immunoglobulin levels nephelometrically determined. Discrepancies appeared in cases with IgA myeloma, macroglobulinemia, and rare types of dysgammaglobulinemia frequently overlooked in serum electrophoresis, IgD myeloma and γ-heavy chain disease. It is suggested that comparison of the γ-globulin levels by the different methods is a simple and useful method of detecting these dysgammaglobulinemias. |