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Abstract

The Discrepancy between Electrophoretic and Nephelometric Determinations of Serum γ-Globulin Level by Keiko Morita, Yasuyuki Okamoto

We studied the significance of discrepancies in correlation between serum γ-globulin levels electrophoretically estimated and immunoglobulin levels nephelometrically determined. Discrepancies appeared in cases with IgA myeloma, macroglobulinemia, and rare types of dysgammaglobulinemia frequently overlooked in serum electrophoresis, IgD myeloma and γ-heavy chain disease. It is suggested that comparison of the γ-globulin levels by the different methods is a simple and useful method of detecting these dysgammaglobulinemias.

DOI: Clin. Lab. 2004;50:415-418