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Abstract

Evaluation of the Urine Protein/Creatinine Ratio Measured with the Dipsticks Clinitek Atlas PRO®12 by Fernando J. Hermida, Sonia Soto, Alfonso J. Benitez

Background: Screening for urine proteins is recommended for the detection of albuminuria in high risk groups. The aim of this study was to compare the Clinitek Atlas PRO®12 reagent urine strip with quantitative methods for the determination of protein/creatinine ratio and to evaluate the usefulness of the semi-quantitative Clinitek Atlas PRO®12 reagent urine strip as a tool in the early detection of albuminuria among the general population.
Methods: Six hundred first morning urine specimens were collected from outpatients with various clinical conditions.
Results: The results showed that the test data for the urine dipstick Clinitek Atlas PRO12 show good agreement with the quantitative measurement of protein, creatinine and protein/creatinine ratio. In addition, this study shows that 97.2% of the samples which gave “normal” protein/creatinine ratios by the semi-quantitative method, showed albumin/creatinine ratio < 30 mg/g by the quantitative methods.
Conclusions: Our results show that Clinitek Atlas PRO12 reagent strips can be used for the purposes of albuminuria screening in the general population.

DOI: 10.7754/Clin.Lab.2015.150727