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Abstract

An Unusual Type of Kidney Stone by Anne-Sophie De Koninck, Luitzen-Albert Groen, Heleen Maes, Alain Gaston Verstraete, Veronique Stove, Joris Richard Delanghe

A very rare case of acetylsulfapyridine nephrolithiasis is presented in a 54-year old female patient who had been prescribed sulfasalazine (6 x 500 mg/day) because of psoriatic arthritis for the last 9 years. The patient’s renal function was only slightly impaired. Reflectance infrared spectroscopy and gas chromatography-mass spectrometry allowed the identification of the chemical nature of the stone. As acetylsulfapyridine is a metabolite of sulfasalazine, administration of the latter drug was the cause of the nephrolithiasis.

DOI: 10.7754/Clin.Lab.2015.150605