Abstract
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Hemophilus Influenzae Infections with Abscess Formation in Adults: a Retrospective Study Covering an Eleven-Year Period
by Muzeyyen Mamal Torun, Hrisi Bahar Tokman, Mehmet Demirci, Sinem Ozdemir, Serdar M. Altinkum, Hatice Cilingir, Filiz Yarimcam Saglam
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Background: The aim of this study was to investigate the presence of Haemophilus influenzae in abscesses in adults and to determine their antibiotic resistance patterns.
Methods: H. influenzae strains isolated from abscesses during an eleven-year period were determined retrospectively and the stored strains were tested for ampicillin, amoxicillin/calvulanic acid, cefuroxime, cefotaxime, ceftriaxone, ciprofloxacin, azithromycin, tetracycline, and imipenem resistance by broth microdilution method. The production of β-lactamase was detected using the nitrocefin disc test and real-time PCR.
Results: A total of 26 H. influenzae isolated strains were found. According to ampicillin resistance and β-lactamase production, 2 strains were determined as BLPAR, 1 strain BLNAR, 1 strain BLPACR, and 22 strains as BLNAS. Cefuroxime resistance was detected in 4 strains, tetracycline resistance was detected in 4 strains, and no resistance to cefotaxime, ceftriaxone, imipenem, azithromycin and levofloxacin was detected.
Conclusions: H. influenzae should be taken into account for the proper management of abscesses.
DOI: 10.7754/Clin.Lab.2015.141011
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