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Abstract |
Imbalance of Interleukin-18 and Interleukin-18 Binding Protein in Patients with IgA Nephropathy Implicating Renal Vasculopathy |
Background: Interleukin-18 (IL-18) is a proinflammatory cytokine which induces interferon-γ production and plays a crucial role in immune systems. IL-18 binding protein (IL-18BP) is a naturally occurring inhibitor of IL18. The aim was to investigate the involvement of IL-18 and IL-18BP in IgA nephropathy (IgAN). |