Clinical Laboratory

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Abstract	Changes in Plasma Intact Parathyroid Hormone Levels Following 24-hour Incubation at Room Temperature as Determined by Roche Electrochemiluminescence PTH Immunoassay by Ashutosh Kumar Arya And Naresh Sachdeva

	Background: Estimation of circulatory PTH is necessary for correct diagnosis of diseases related to the parathyroid gland, bone, and kidney. Methods: Roche Electrochemiluminescence PTH immunoassay was used to measure changes in plasma iPTH concentration in 100 random samples following a 24 hours incubation at room temperature. Results: Low to normal iPTH concentration individuals showed higher decrease in iPTH concentration as compared to individuals with elevated PTH and the rate of PTH degradation was significantly higher (p < 0.05) in the low to normal PTH group. Conclusions: Blood samples from suspected hypo- or normo-parathyroid subjects should be analyzed as soon as possible as a little degradation of PTH at room temperature could influence their clinical interpretation. DOI: 10.7754/Clin.Lab.2013.130419

Abstract