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Abstract |
Plasma Annexin A5, Anti-Annexin A5 Antibodies and Annexin A5 Polymorphism in Egyptian Female Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
Background: Annexin A5 exhibits anticoagulant properties that appear to be defective in patients with antiphospholipid syndrome (APS) resulting in repeated thrombosis and recurrent pregnancy loss (RPL). APS occurs frequently in association with systemic lupus erythematosus (SLE). The present study aimed to find out a possible relationship between annexin A5 (gene polymorphism, antibodies or plasma level) and the pathophysiology of SLE, APS and RPL. |