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Abstract |
Evaluation of the Fluorotype MTB Assay for the Rapid and Reliable Detection of Mycobacterium Tuberculosis in Respiratory Tract Specimens |
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We performed the first evaluation study of the new FluoroType MTB assay, a HyBeacon based nucleic acid amplification test for the direct detection of Mycobacterium tu-berculosis in respiratory tract specimens. Using mycobacterial culture as a refer-ence, 661 specimens were tested. Sensitivity and specificity were 95.1% and 96.4% for all specimens, sensitivity was 100% for smear-positive and 84.6% for smear negative specimens, respectively. The FluoroType MTB assay showed fast and accurate results within 3 hours, including DNA extraction. |
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