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Abstract |
Defective NF-kB Transcription Factor as the Mediator of Inflammatory Responses: A Study on Depressed Iranian Medical Students |
Background: NF-kB is a transcription factor that is a downstream target of several cell signaling systems including TLRs. Defective expression of the molecule can lead to inappropriate immune responses. Previous studies revealed that depression can affect immune responses, but its molecular mechanisms are yet to be fully understood. Thus, the main aim of this study was to identify if mRNA levels of NF-kB are changed in the PBMCs isolated from Iranian depressed medical students.
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