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Abstract

Understanding the Clinical Biochemistry of N-Terminal Pro-B-Type Natriuretic Peptide: the Prerequisite for Its Optimal Clinical Use by Mauro Panteghini, Aldo Clerico

With the introduction of the first rapid, fully automated assay for N-terminal pro-B-type natriuretic peptide (NtproBNP) determination, clinical laboratories are now able to transfer a number of preliminary information derived from pilot research experiences to the context of clinical cardiology. Some confounding factors may, however, affect the interpretation of the Nt-proBNP test and its clinical value. The objective of this review is to highlight and discuss these potentially confounding variables.

DOI: Clin. Lab. 2004;50:325-331