Abstract
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Evaluation of Pneumococcal PCR and Urinary Antigen Detection in Children
by Aslinur Özkaya Parlakay, Mehmet Ceyhan, Melda Çelik, Yasemin Özsürekci, Eda Karadağ Öncel, Gulnar Sensoy, Nursen Belet, Melike Keser Emiroglu, Ahmet Emre Aycan, Kumsal Çağlar
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Background: The rapid detection of Streptococcus pneumoniae could assist in the man-agement of pneumococcal infections. The Binax NOW S. pneumoniae test is a rapid im-munochromatographic test for this purpose.
Methods: Multiplex PCR in parapneumonic pleural effusion fluid (PPEF) and cerebro-spinal fluid (CSF) with Bi¬nax NOW urinary pneumococcal antigen test (PAT) from 80 children was compared in this study.
Results: PAT had a sensitivity of 36.4%, specificity of 97.3%, in CSF. PAT had a sensitivity of 50%, specificity of 81% for parapneumonic pleural effusion fluid.
Conclusýons: When rapid management of a serious infection is needed the Binax NOW test could be a reliable method for the exclusion of S. pneumoniae infection.
DOI: 10.7754/Clin.Lab.2012.121206
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