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Abstract

Peripheral Blood and Bone Marrow Cells Cultivated in Novy-Mcneal-Nicolle Medium for Visceral Leishmaniosis Diagnosis Revealed Rhodotorula Fungemia in an AIDS Patient with Lymphoma by Andre Paugam, Agathe Lebuisson, Olivier Lortholary, Marie-Therese Baixench, Fanny Lanternier

Rhodotorula is a ubiquitous yeast that can infect immunocompromised patients. Here, we present the case of a 45-year-old patient with AIDS who developed a Rhodotorula mucilaginosa fungemia. The patient had a past history of visceral leishmaniasis (VL) and was hospitalised to receive chemotherapy for a B-cell lymphoma of the sino-nasal cavities. The patient had no fever and no signs of VL. A systematic research for Leishmania by blood and bone marrow cultures was made and he received liposomal amphtotericin B (3 mg/kg in a single dose) to prevent a VL relapse. Rhodotorula fungemia was accidentally detected after 17 days of blood culture using a specific me-dium for leishmaniasis diagnosis. This long culture incubation time was probably facilitated by amphotericin B treatment. Rhodotorula is an emerging pathogen that may escape detection due its slow growth in culture.

DOI: 10.7754/Clin.Lab.2012.120711